Overview of Chosen Chemical Compounds and Intermediates

Overview of Chosen Chemical Compounds and Intermediates

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1. Pharmaceutical Intermediates
Bortezomib Acid Impurity: This is an impurity associated with bortezomib, a proteasome inhibitor used in the remedy of several myeloma. Its synthesis or research is essential for making sure the purity and basic safety from the drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-seven): A precursor during the synthesis of abiraterone acetate, a drug Employed in the cure of prostate cancer by inhibiting androgen output.
Imatinib Intermediate (CAS NO. 152460-10-one): A important compound in the synthesis of imatinib, a drug that targets unique sorts of cancer, including Long-term myelogenous leukemia (CML).
Docetaxel Intermediate: A compound used in the synthesis of docetaxel, a chemotherapy medication that treats several cancers including breast, lung, and prostate most cancers.
2. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, 8): They are intermediates from the synthesis of gemcitabine, an anti-cancer drug. Their review is crucial for optimizing the manufacturing system and making certain superior purity.
Lapatinib Intermediate (CAS NO. 231278-84-5): Lapatinib is applied to treat breast cancer, and these intermediates are involved with its production.
Fulvestrant Intermediates: Fulvestrant can be an estrogen receptor antagonist used tert-butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate in the treatment method of breast most cancers. Various intermediates help in the synthesis of the drug.
Paclitaxel Aspect Chain Acid (CAS NO. 949023-sixteen-nine): This intermediate is used in the synthesis of paclitaxel, a chemotherapy drug productive in managing cancers like ovarian, breast, and lung cancer.
3. Other Noteworthy Compounds
Irinotecan Hydrochloride Trihydrate (CAS NO. 136572-09-three): A chemotherapy drug Utilized in the procedure of colorectal cancer and tiny mobile lung most cancers.
three-Amino-one-hydroxyadamantane (CAS 702-eighty two-nine): This compound is linked to the synthesis of adamantane derivatives, that have numerous programs, which include antiviral Attributes.
Vildagliptin Intermediates: Employed in the production of vildagliptin, an oral drug for kind 2 CAS NO.132127-34-5 diabetes that inhibits the enzyme DPP-four to control blood sugar concentrations.
four. Miscellaneous Compounds
D-Gluconic Acid δ-Lactone (CAS NO. 61259-forty eight-1): This compound is associated with the synthesis of various gluconic acid derivatives, that happen to be used in meals, pharmaceutical, and industrial apps.
Canagliflozin Intermediate two: A precursor from the synthesis of canagliflozin, a medication used to handle variety 2 diabetes by inhibiting sodium-glucose co-transporter 2 (SGLT2).